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¹øÈ£ 148 ÀÛ¼ºÀÚ ¿î¿µÀÚ ³¯Â¥ 2005-08- Á¶È¸ 2557
Á¦ ¸ñ : Re:ƯÇã È®ÀÎ Á» ºÎŹ µå¸±²²¿ä

Çѱ¹Æ¯Çã¹øÈ£¿¡ ´ëÇÑ ±â¼ú ³»¿ëÀº ´ÙÀ½°ú °°½À´Ï´Ù.

°¨±Ö·ù °úÇÇ ÃßÃâ¹°, À̷κÎÅÍ ºÐ¸® Á¤Á¦µÈ Ç콺Æ丮µò ¶Ç´Â ³ª¸°ÁøÀ» Æ÷ÇÔÇÏ´Â ½ÉÇ÷°ü Áúȯ ¿¹¹æ¹× Ä¡·áÁ¦ Á¶¼º¹°
(Compositions For the Prevention and Therapy of Cardiovascular Disease Containing Extract of Citrus Fruit Peel, Hesperidin or Naringin)

ÃÊ·Ï º» ¹ß¸íÀº °¨±Ö·ù °úÇÇ ÃßÃâ¹°, À̷κÎÅÍ ºÐ¸® Á¤Á¦µÈ Ç콺Æ丮µò ¶Ç´Â ³ª¸°ÁøÀ» ÇÔÀ¯ÇÏ´Â ½ÉÇ÷°ü Áúȯ ¿¹¹æ ¹× Ä¡·áÁ¦ Á¶¼º¹°¿¡ °üÇÑ °ÍÀ¸·Î, °¨±Ö·ù °úÇÇ ÃßÃâ¹° ¹× À̷κÎÅÍ ºÐ¸® Á¤Á¦µÈ Ç콺Æ丮µò ¹× ³ª¸°ÁøÀº HMG-CoA ȯ¿øÈ¿¼ÒÀÇ È°¼ºÀ» ÀúÇØÇÏ¿© Ç÷Áß ÄÝ·¹½ºÅ×·Ñ ³óµµ¸¦ ÀúÇϽÃÅ´À¸·Î½á ½ÉÀ庴, µ¿¸Æ°æÈ­Áõ µîÀÇ ½ÉÇ÷°ü ÁúȯÀÇ ¿¹¹æ ¹× Ä¡·áÁ¦·Î À¯¿ëÇÏ°Ô »ç¿ëµÉ ¼ö ÀÖ´Ù.

´ëǥû±¸Ç× °¨±Ö·ù °úÇÇ ÃßÃâ¹°À» Æ÷ÇÔÇÏ´Â ½ÉÇ÷°ü ÁúȯÀÇ ¿¹¹æ ¹× Ä¡·áÁ¦ Á¶¼º¹°.°¨±Ö·ù °úÇÇ ÃßÃâ¹°À» Æ÷ÇÔÇÏ´Â ÇÏÀ̵å·Ï½Ã¸ÞÆ¿±Û·çŸ¸±-ÄÚ¿¡ÀÌ(hydroxymethylglutaryl-CoA; HMG-CoA)ȯ¿øÈ¿¼Ò È°¼º ÀúÇØ¿ë Á¶¼º¹°.

¹Ì±¹Æ¯Çã¹øÈ£´Â »ó±â Çѱ¹ ƯÇã¿¡ ´ëÇÑ ¹Ì±¹ÀÇ Ãâ¿ø°ÇÀ̶ó°í »ý°¢À» ÇÏ½Ã¸é µÇ°Ú½À´Ï´Ù.

Naringin and naringenin as 3-hydroxy-3-methylglutaryl CoA(HMG-CoA) reductase inhibitor


Abstract
A method for inhibiting the activity of 3-hydroxy-3-methylglutaryl CoA(HMG--CoA) reductase in mammals is disclosed comprising administering naringin or naringenin thereto.

Ãß°¡ÀûÀÎ Áú¹® »çÇ×ÀÌ ÀÖÀ¸½Ã¸é ´Ù½Ã ÇϽñ⠹ٶø´Ï´Ù.

 
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